Ever wondered if hair loss treatments such as finasteride worked?

Well, according to menscript, an online health clinic specialises in offering hair loss treatments in the UK, it does.

Male pattern hair loss, or androgenetic alopecia (AGA), produces progressive, visible thinning of scalp hair in genetically susceptible men. This progressive miniaturisation of hair follicles is due to a shortened duration of the anagen, growth phase and a reduction in the size of the hair matrix. This causes gradual transformation of large terminal follicles to miniaturised follicles that produce shorter and finer hairs. In susceptible scalp follicles, dihydrotestosterone (DHT) binds to the androgen receptor and the hormone-receptor complex in some manner activates genes responsible for the miniaturisation process. Compared with the occipital scalp, the frontal scalp of young men with AGA contains higher levels of DHT, type 2 5a-reductase, and androgen receptor.

Finasteride is a type 2 5a-reductase inhibitor shown to decrease levels of DHT in both scalp and serum, and clinical trials have shown that finasteride slows progressive hair loss and increases hair growth in men with predominantly vertex or frontal AGA. A double-blind, placebo-controlled study of men with AGA found that finasteride (1 mg/d) slowed hair loss and increased hair growth over the course of 5 years. Similarly, a placebo-controlled study followed by a 1-year open extension showed that finasteride (1 mg/d) slowed hair loss and increased hair growth in the frontoparietal scalp.

For more information see the full article on Finasteride for male hair loss